Target:Endomucin
Gene Name:EMCN
Protein Name:Endomucin
Human Gene Id:51705
Human Swiss Prot No:Q9ULC0
Mouse Gene Id:59308
Mouse Swiss Prot No:Q9R0H2
Rat Gene Id:295490
Rat Swiss Prot No:Q6AY82
Immunogen:The antiserum was produced against synthesized peptide derived from human Mucin-14. AA range:201-250
Specificity:Endomucin Polyclonal Antibody detects endogenous levels of Endomucin protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:EMCN;EMCN2;MUC14;Endomucin;Endomucin-2;Gastric cancer antigen Ga34;Mucin-14;MUC-14
Molecular Weight(Da):27kD
Background:endomucin(EMCN) Homo sapiens EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008],
Function:function:Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.,PTM:Highly O-glycosylated. Sialic acid-rich glycoprotein.,subcellular location:Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.,tissue specificity:Expressed in heart, kidney and lung.,
Subcellular Location:[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.; [Isoform 2]: Secreted .
Expression:Expressed in heart, kidney and lung.