Target:ELOVL1
Fields:Fatty acid elongation;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Fatty acid metabolism
Gene Name:ELOVL1
Protein Name:Elongation of very long chain fatty acids protein 1
Human Gene Id:64834
Human Swiss Prot No:Q9BW60
Mouse Gene Id:54325
Mouse Swiss Prot No:Q9JLJ5
Immunogen:The antiserum was produced against synthesized peptide derived from human ELOVL1. AA range:101-150
Specificity:ELOVL1 Polyclonal Antibody detects endogenous levels of ELOVL1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:ELOVL1;SSC1;CGI-88;Elongation of very long chain fatty acids protein 1;3-keto acyl-CoA synthase ELOVL1;ELOVL fatty acid elongase 1;ELOVL FA elongase 1
Observed Band(KD):33kD
Background:domain:The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.,function:Could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. May catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative.,similarity:Belongs to the ELO family.,
Function:domain:The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.,function:Could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. May catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative.,similarity:Belongs to the ELO family.,
Subcellular Location:Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Expression:Ubiquitous.