Target：Egr-3

Fields：C-type lectin receptor signaling pathway;Hepatitis B;Viral carcinogenesis

Gene Name：EGR3

Protein Name：Early growth response protein 3

Human Gene Id：1960

Human Swiss Prot No：Q06889

Mouse Gene Id：13655

Mouse Swiss Prot No：P43300

Rat Gene Id：25148

Rat Swiss Prot No：P43301

Immunogen：The antiserum was produced against synthesized peptide derived from human EGR3. AA range:338-387

Specificity：Egr-3 Polyclonal Antibody detects endogenous levels of Egr-3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：EGR3;PILOT;Early growth response protein 3;EGR-3;Zinc finger protein pilot

Molecular Weight(Da)：43kD

Background： This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010],

Function：developmental stage:In T-cells, expressed 20 minutes following activation.,function:Probable transcription factor involved in muscle spindle development.,similarity:Belongs to the EGR C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,

Subcellular Location：Nucleus .

Expression： Brain,Peripheral blood T-cell,