Target：AR-α1D

Fields：Calcium signaling pathway;cGMP-PKG signaling pathway;Neuroactive ligand-receptor interaction;Adrenergic signaling in cardiomyocytes;Vascular smooth muscle contraction;Salivary secretion

Gene Name：ADRA1D

Protein Name：Alpha-1D adrenergic receptor

Human Gene Id：146

Human Swiss Prot No：P25100

Mouse Swiss Prot No：P97714

Immunogen：The antiserum was produced against synthesized peptide derived from human ADRA1D. AA range:451-500

Specificity：AR-α1D Polyclonal Antibody detects endogenous levels of AR-α1D protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ADRA1D;ADRA1A;Alpha-1D adrenergic receptor;Alpha-1A adrenergic receptor;Alpha-1D adrenoreceptor;Alpha-1D adrenoceptor;Alpha-adrenergic receptor 1a

Molecular Weight(Da)：60kD

Background： Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008],

Function：function:This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression： Hippocampus,Placenta,Prostate,