Target：Arylsulfatase K

Gene Name：ARSK

Protein Name：Arylsulfatase K

Human Gene Id：153642

Human Swiss Prot No：Q6UWY0

Mouse Gene Id：77041

Mouse Swiss Prot No：Q9D2L1

Rat Gene Id：365619

Rat Swiss Prot No：Q32KJ2

Immunogen：The antiserum was produced against synthesized peptide derived from human ARSK. AA range:481-530

Specificity：Arylsulfatase K Polyclonal Antibody detects endogenous levels of Arylsulfatase K protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ARSK;TSULF;Arylsulfatase K;ASK;Telethon sulfatase

Observed Band(KD)：62kD

Background： Sulfatases (EC 3.1.5.6), such as ARSK, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).[supplied by OMIM, Mar 2008],

Function：cofactor:Binds 1 calcium ion per subunit.,PTM:The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.,similarity:Belongs to the sulfatase family.,

Subcellular Location：Secreted . Lysosome .

Expression：Expressed at high levels in the placenta and pancreas (PubMed:23986440). Expressed at intermediate levels in the lung, brain, heart, liver and kidney and at low levels in the muscle (PubMed:23986440).