Target：Arrestin-C

Gene Name：ARR3

Protein Name：Arrestin-C

Human Gene Id：407

Human Swiss Prot No：P36575

Mouse Swiss Prot No：Q9EQP6

Immunogen：The antiserum was produced against synthesized peptide derived from human ARRC. AA range:339-388

Specificity：Arrestin-C Polyclonal Antibody detects endogenous levels of Arrestin-C protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ARR3;ARRX;CAR;Arrestin-C;Cone arrestin;C-arrestin;cArr;Retinal cone arrestin-3;X-arrestin

Observed Band(KD)：40kD

Background： The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016],

Function：function:May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins.,similarity:Belongs to the arrestin family.,tissue specificity:Inner and outer segments, and the inner plexiform regions of the retina.,

Subcellular Location：Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment .

Expression：Inner and outer segments, and the inner plexiform regions of the retina.