Target：Egr-2
Fields：Apelin signaling pathway;GnRH signaling pathway;Parathyroid hormone synthesis, secretion and action;AGE-RAGE signaling pathway in diabetic complications;Prion disease;Human T-cell leukemia virus 1 infection
Gene Name：EGR2
Protein Name：Early growth response protein 2
Human Gene Id：1958/1959
Human Swiss Prot No：P18146/P11161
Mouse Gene Id：13653/13654
Rat Gene Id：24330/114090
Rat Swiss Prot No：P08154/P51774
Immunogen：The antiserum was produced against synthesized peptide derived from human EGR1/2. AA range:371-420
Specificity：Egr-2 Polyclonal Antibody detects endogenous levels of Egr-2 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：EGR1;KROX24;ZNF225;Early growth response protein 1;EGR-1;AT225;Nerve growth factor-induced protein A;NGFI-A;Transcription factor ETR103;Transcription factor Zif268;Zinc finger protein 225;Zinc finger protein Krox-24;EGR2;KROX20
Observed Band(KD)：50kD
Background： The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014],
Function：function:Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.,induction:By growth factors.,similarity:Belongs to the EGR C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,
Subcellular Location：Nucleus . Cytoplasm .
Expression：Detected in neutrophils (at protein level).
