Target：EGFL4

Fields：Hedgehog signaling pathway

Gene Name：MEGF8

Protein Name：Multiple epidermal growth factor-like domains protein 8

Human Gene Id：1954

Human Swiss Prot No：Q7Z7M0

Mouse Swiss Prot No：P60882

Immunogen：The antiserum was produced against synthesized peptide derived from human MEGF8. AA range:1243-1292

Specificity：EGFL4 Polyclonal Antibody detects endogenous levels of EGFL4 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：MEGF8;C19orf49;EGFL4;KIAA0817;Multiple epidermal growth factor-like domains protein 8;Multiple EGF-like domains protein 8;Epidermal growth factor-like protein 4;EGF-like protein 4

Observed Band(KD)：255kD

Background： The protein encoded by this gene is a single-pass type I membrane protein of unknown function that contains several EGF-like domains, Kelch repeats, and PSI domains. Defects in this gene are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],

Function：similarity:Contains 12 Kelch repeats.,similarity:Contains 2 CUB domains.,similarity:Contains 4 laminin EGF-like domains.,similarity:Contains 5 EGF-like domains.,similarity:Contains 7 PSI domains.,

Subcellular Location：Membrane ; Single-pass type I membrane protein .

Expression： Brain,Pancreas,Plasma,