Target：Dyrk4

Gene Name：DYRK4

Protein Name：Dual specificity tyrosine-phosphorylation-regulated kinase 4

Human Gene Id：8798

Human Swiss Prot No：Q9NR20

Mouse Swiss Prot No：Q8BI55

Immunogen：Synthesized peptide derived from Dyrk4 . at AA range: 350-430

Specificity：Dyrk4 Polyclonal Antibody detects endogenous levels of Dyrk4 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：DYRK4;Dual specificity tyrosine-phosphorylation-regulated kinase 4

Observed Band(KD)：60kD

Background： This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013],

Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Possible non-essential role in spermiogenesis.,PTM:Autophosphorylated on tyrosine residues.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.,similarity:Contains 1 protein kinase domain.,

Subcellular Location：[Isoform 1]: Cytoplasm .; [Isoform 4]: Cytoplasm . Nucleus .

Expression： Brain,Kidney,Lung,Testis,