Target：Dynein LC 4

Fields：Amyotrophic lateral sclerosis;Huntington disease;Pathways of neurodegeneration - multiple diseases

Gene Name：DNAL4

Protein Name：Dynein light chain 4 axonemal

Human Gene Id：10126

Human Swiss Prot No：O96015

Mouse Gene Id：54152

Mouse Swiss Prot No：Q9DCM4

Immunogen：The antiserum was produced against synthesized peptide derived from human DNAL4. AA range:1-50

Specificity：Dynein LC 4 Polyclonal Antibody detects endogenous levels of Dynein LC 4 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：DNAL4;Dynein light chain 4; axonemal

Molecular Weight(Da)：12kD

Background： This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. [provided by RefSeq, Dec 2014],

Function：function:Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.,similarity:Belongs to the dynein light chain family.,subunit:Consists of at least two heavy chains and a number of intermediate and light chains.,

Subcellular Location：Cytoplasm, cytoskeleton, cilium axoneme .

Expression： Lung,Skin,Testis,