Target:Dynein LC 2B
Fields:Salmonella infection
Gene Name:DYNLRB2
Protein Name:Dynein light chain roadblock-type 2
Human Gene Id:83657
Human Swiss Prot No:Q8TF09
Mouse Gene Id:75465
Mouse Swiss Prot No:Q9DAJ5
Immunogen:The antiserum was produced against synthesized peptide derived from human DYNLRB2. AA range:21-70
Specificity:Dynein LC 2B Polyclonal Antibody detects endogenous levels of Dynein LC 2B protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:DYNLRB2;DNCL2B;DNLC2B;ROBLD2;Dynein light chain roadblock-type 2;Dynein light chain 2B; cytoplasmic;Roadblock domain-containing protein 2
Molecular Weight(Da):11kD
Background:function:May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport.,miscellaneous:Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients.,similarity:Belongs to the GAMAD family.,tissue specificity:High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.,
Function:function:May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport.,miscellaneous:Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients.,similarity:Belongs to the GAMAD family.,tissue specificity:High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.,
Subcellular Location:Cytoplasm, cytoskeleton.
Expression:High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.