Target：DYN3

Fields：Phospholipase D signaling pathway;Endocytosis;Synaptic vesicle cycle;Endocrine and other factor-regulated calcium reabsorption;Bacterial invasion of epithelial cells

Gene Name：DNM3 KIAA0820

Protein Name：Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)

Human Gene Id：26052

Human Swiss Prot No：Q9UQ16

Mouse Swiss Prot No：Q8BZ98

Rat Swiss Prot No：Q08877

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：DYN3 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：95kD

Background：dynamin 3(DNM3) Homo sapiens This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

Function：catalytic activity:GTP + H(2)O = GDP + phosphate.,function:Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.,similarity:Belongs to the dynamin family.,similarity:Contains 1 GED domain.,similarity:Contains 1 PH domain.,subcellular location:Microtubule-associated.,

Subcellular Location：Cytoplasm . Cytoplasm, cytoskeleton . Microtubule-associated. .

Expression： Brain,Kidney,