Target：DRAM1

Gene Name：DRAM1 DRAM

Protein Name：DNA damage-regulated autophagy modulator protein 1 (Damage-regulated autophagy modulator)

Human Gene Id：55332

Human Swiss Prot No：Q8N682

Mouse Swiss Prot No：Q9DC58

Immunogen：Synthesized peptide derived from human protein . at AA range: 151-200

Specificity：DRAM1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：26kD

Background： This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008],

Function：autophagy, apoptosis, cell death, programmed cell death, death,

Subcellular Location：Lysosome membrane ; Multi-pass membrane protein .