Target:DRAK2
Gene Name:STK17B
Protein Name:Serine/threonine-protein kinase 17B
Human Gene Id:9262
Human Swiss Prot No:O94768
Mouse Gene Id:98267
Mouse Swiss Prot No:Q8BG48
Rat Gene Id:170904
Rat Swiss Prot No:Q91XS8
Immunogen:The antiserum was produced against synthesized peptide derived from human STK17B. AA range:251-300
Specificity:DRAK2 Polyclonal Antibody detects endogenous levels of DRAK2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:STK17B;DRAK2;Serine/threonine-protein kinase 17B;DAP kinase-related apoptosis-inducing protein kinase 2
Observed Band(KD):45kD
Background:catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Acts as a positive regulator of apoptosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CHP causing CHP to translocate from the Golgi to the nucleus.,tissue specificity:Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.,
Function:catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Acts as a positive regulator of apoptosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CHP causing CHP to translocate from the Golgi to the nucleus.,tissue specificity:Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.,
Subcellular Location:Nucleus . Cell membrane . Endoplasmic reticulum-Golgi intermediate compartment . Colocalizes with STK17B at the plasma membrane. .
Expression:Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.