Target:DPP7
Gene Name:DPP7
Protein Name:Dipeptidyl peptidase 2
Human Gene Id:29952
Human Swiss Prot No:Q9UHL4
Mouse Swiss Prot No:Q9ET22
Immunogen:Synthesized peptide derived from the C-terminal region of human DPP7.
Specificity:DPP7 Polyclonal Antibody detects endogenous levels of DPP7 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:DPP7;DPP2;QPP;Dipeptidyl peptidase 2;Dipeptidyl aminopeptidase II;Dipeptidyl peptidase 7;Dipeptidyl peptidase II;DPP II;Quiescent cell proline dipeptidase
Observed Band(KD):54kD
Background: The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. [provided by RefSeq, Jul 2008],
Function:catalytic activity:Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides.,function:Plays an important role in the degradation of some oligopeptides.,PTM:N-glycosylated.,similarity:Belongs to the peptidase S28 family.,subunit:Homodimer.,
Subcellular Location:Lysosome . Cytoplasmic vesicle . Secreted .
Expression:Detected in seminal plasma (at protein level).