Target:DPF2
Gene Name:DPF2
Protein Name:Zinc finger protein ubi-d4
Human Gene Id:5977
Human Swiss Prot No:Q92785
Mouse Gene Id:19708
Mouse Swiss Prot No:Q61103
Immunogen:The antiserum was produced against synthesized peptide derived from human REQU. AA range:151-200
Specificity:DPF2 Polyclonal Antibody detects endogenous levels of DPF2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:DPF2;BAF45D;REQ;UBID4;Zinc finger protein ubi-d4;Apoptosis response zinc finger protein;BRG1-associated factor 45D;BAF45D;D4; zinc and double PHD fingers family 2;Protein requiem
Observed Band(KD):44kD
Background: The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008],
Function:function:May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells.,similarity:Belongs to the requiem/DPF family.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 2 PHD-type zinc fingers.,subcellular location:30% nuclear. 70% cytoplasmic.,tissue specificity:Ubiquitous.,
Subcellular Location:Nucleus . Cytoplasm .
Expression:Ubiquitous.