Target：GCM2

Fields：Parathyroid hormone synthesis, secretion and action

Gene Name：GCM2

Protein Name：GCM2

Human Gene Id：9247

Human Swiss Prot No：O75603

Mouse Gene Id：107889

Mouse Swiss Prot No：O09102

Immunogen：Synthesized peptide derived from human GCM2. at AA range: 21-70

Specificity：GCM2 Polyclonal Antibody detects endogenous levels of GCM2

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000, ELISA 1:10000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：Chorion-specific transcription factor GCMb (hGCMb) (GCM motif protein 2) (Glial cells missing homolog 2)

Observed Band(KD)：56kD

Background： This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism. [provided by RefSeq, Jul 2008],

Function：function:Probable transcriptional regulator.,similarity:Contains 1 GCM DNA-binding domain.,

Subcellular Location：Nucleus .

Expression： Brain,Fetal brain,