Target：DnaJB4

Gene Name：DNAJB4

Protein Name：DnaJ homolog subfamily B member 4

Human Gene Id：11080

Human Swiss Prot No：Q9UDY4

Mouse Gene Id：67035

Mouse Swiss Prot No：Q9D832

Immunogen：The antiserum was produced against synthesized peptide derived from human DNAJB4. AA range:91-140

Specificity：DnaJB4 Polyclonal Antibody detects endogenous levels of DnaJB4 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：DNAJB4;DNAJW;HLJ1;DnaJ homolog subfamily B member 4;Heat shock 40 kDa protein 1 homolog;HSP40 homolog;Heat shock protein 40 homolog;Human liver DnaJ-like protein

Observed Band(KD)：38kD

Background： The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],

Function：induction:By heat shock.,similarity:Contains 1 J domain.,

Subcellular Location：Cytoplasm . Cell membrane . Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645.

Expression：Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver.