Target:DDT
Gene Name:DDT
Protein Name:D-dopachrome decarboxylase (EC 4.1.1.84) (D-dopachrome tautomerase) (Phenylpyruvate tautomerase II)
Human Gene Id:1652
Human Swiss Prot No:P30046
Mouse Gene Id:13202
Mouse Swiss Prot No:O35215
Rat Swiss Prot No:P80254
Immunogen:Synthetic peptide from human protein at AA range: 50-90
Specificity:The antibody detects endogenous DDT
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:D-dopachrome decarboxylase (EC 4.1.1.84;D-dopachrome tautomerase;Phenylpyruvate tautomerase II)
Background: D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22. [provided by RefSeq, Jul 2008],
Function:catalytic activity:D-dopachrome = 5,6-dihydroxyindole + CO(2).,function:Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).,similarity:Belongs to the MIF family.,subunit:Homotrimer.,
Subcellular Location:Cytoplasm .
Expression:Highly expressed in the liver and at lower levels in the heart, lung and pancreas.