Target：DC1L1

Fields：Phagosome;Vasopressin-regulated water reabsorption;Salmonella infection

Gene Name：DYNC1LI1 DNCLI1

Protein Name：Cytoplasmic dynein 1 light intermediate chain 1 (LIC1) (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic)

Human Gene Id：51143

Human Swiss Prot No：Q9Y6G9

Mouse Swiss Prot No：Q8R1Q8

Rat Swiss Prot No：Q9QXU8

Immunogen：Synthesized peptide derived from part region of human protein AA range: 292-342

Specificity：DC1L1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：57kD

Background： The protein encoded by this gene belongs to light intermediate subunit family, whose members are components of the multiprotein cytoplasmic dynein complex, which is involved in intracellular trafficking and chromosome segregation during mitosis. The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles. The protein may also mediate binding to other cargo molecules to facilitate intracellular vesicle trafficking. [provided by RefSeq, Jul 2016],

Function：function:May play a role in binding dynein to membranous organelles or chromosomes. May associate with the heavy chains in the dynein head where they might regulate enzyme activity.,PTM:Phosphorylated.,similarity:Belongs to the dynein light intermediate chain family.,subunit:Consists of at least 3 heavy chains (alpha, beta and gamma), 2 intermediate chains and 8 light chains.,

Subcellular Location：Cytoplasm . Chromosome, centromere, kinetochore . Cytoplasm, cytoskeleton, spindle pole .

Expression： Cerebellum,Coronary artery,Epithelium,Human testis,