Target：CYP2U1

Fields：Fatty acid degradation;Arachidonic acid metabolism;Metabolic pathways

Gene Name：CYP2U1

Protein Name：Cytochrome P450 2U1

Human Gene Id：113612

Human Swiss Prot No：Q7Z449

Mouse Gene Id：71519

Mouse Swiss Prot No：Q9CX98

Rat Gene Id：310848

Rat Swiss Prot No：Q4V8D1

Immunogen：The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2U1. AA range:281-330

Specificity：CYP2U1 Polyclonal Antibody detects endogenous levels of CYP2U1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CYP2U1;Cytochrome P450 2U1

Observed Band(KD)：61kD

Background： This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008],

Function：catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,developmental stage:Expressed in fetal thymus.,function:Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Widely expressed with stronger expression in thymus, heart and cerebellum.,

Subcellular Location：Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein . Mitochondrion inner membrane ; Multi-pass membrane protein .

Expression：Widely expressed with stronger expression in thymus, heart and cerebellum.