Target：CRP

Gene Name：CRP

Protein Name：C-reactive protein

Human Gene Id：1401

Human Swiss Prot No：P02741

Mouse Swiss Prot No：P14847

Rat Gene Id：25419

Rat Swiss Prot No：P48199

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human CRP. AA range:101-150

Specificity：CRP Polyclonal Antibody detects endogenous levels of CRP protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CRP;PTX1;C-reactive protein

Observed Band(KD)：25kD

Background：C-reactive protein(CRP) Homo sapiens The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009],

Function：cofactor:Binds 2 calcium ions per subunit.,function:Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.,induction:The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6.,mass spectrometry: Ref.14,miscellaneous:This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium.,online information:C-reactive protein entry,online information:No more Christmas pudding? - Issue 30 of January 2003,similarity:Belongs to the pentaxin family.,similarity:Contains 1 pentaxin dom

Subcellular Location：Secreted.

Expression：Found in plasma.