Target:CRBP-III
Gene Name:RBP5
Protein Name:Retinol-binding protein 5
Human Gene Id:83758
Human Swiss Prot No:P82980
Immunogen:The antiserum was produced against synthesized peptide derived from human CRBP III. AA range:10-59
Specificity:CRBP-III Polyclonal Antibody detects endogenous levels of CRBP-III protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RBP5;Retinol-binding protein 5;Cellular retinol-binding protein III;CRBP-III;HRBPiso
Molecular Weight(Da):16kD
Background:retinol binding protein 5(RBP5) Homo sapiens The protein encoded by this gene is a cellular retinol-binding protein expressed highly in kidney and liver. Down-regulation of the encoded protein in hepatocellular carcinoma was associated with large tumor size and poor patient survival rates. [provided by RefSeq, Jul 2016],
Function:domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Intracellular transport of retinol.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,tissue specificity:Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level).,
Subcellular Location:Cytoplasm .
Expression:Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level).