Target:CPNS2
Gene Name:CAPNS2
Protein Name:Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2)
Human Gene Id:84290
Human Swiss Prot No:Q96L46
Mouse Swiss Prot No:Q9D7J7
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:CPNS2 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):27kD
Background:function:Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.,similarity:Contains 4 EF-hand domains.,subcellular location:Translocates to the plasma membrane upon calcium binding.,subunit:Heterodimer of a large (catalytic) and a small (regulatory) subunit.,
Function:function:Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.,similarity:Contains 4 EF-hand domains.,subcellular location:Translocates to the plasma membrane upon calcium binding.,subunit:Heterodimer of a large (catalytic) and a small (regulatory) subunit.,
Subcellular Location:Cytoplasm . Cell membrane . Translocates to the plasma membrane upon calcium binding. .
Expression: Urinary bladder carcinoma,