Target:CPN reg
Gene Name:CPN2
Protein Name:Carboxypeptidase N subunit 2
Human Gene Id:1370
Human Swiss Prot No:P22792
Mouse Swiss Prot No:Q9DBB9
Immunogen:Synthesized peptide derived from the C-terminal region of human CPN reg.
Specificity:CPN reg Polyclonal Antibody detects endogenous levels of CPN reg protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CPN2;ACBP;Carboxypeptidase N subunit 2;Carboxypeptidase N 83 kDa chain;Carboxypeptidase N large subunit;Carboxypeptidase N polypeptide 2;Carboxypeptidase N regulatory subunit
Observed Band(KD):60kD
Background:function:The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.,PTM:Whether or not any Cys residues participate in intrachain bonds is unknown, but they do not form interchain disulfide bonds with the 50 kDa catalytic subunit.,similarity:Contains 13 LRR (leucine-rich) repeats.,subunit:Tetramer of two catalytic chains and two glycosylated inactive chains.,
Function:function:The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.,PTM:Whether or not any Cys residues participate in intrachain bonds is unknown, but they do not form interchain disulfide bonds with the 50 kDa catalytic subunit.,similarity:Contains 13 LRR (leucine-rich) repeats.,subunit:Tetramer of two catalytic chains and two glycosylated inactive chains.,
Subcellular Location:Secreted.
Expression: Hepatoblastoma,Plasma,