Target：COX19

Fields：Thermogenesis

Gene Name：COX19

Protein Name：Cytochrome c oxidase assembly protein COX19

Human Gene Id：90639

Human Swiss Prot No：Q49B96

Mouse Gene Id：68033

Mouse Swiss Prot No：Q8K0C8

Immunogen：The antiserum was produced against synthesized peptide derived from human COX19. AA range:10-59

Specificity：COX19 Polyclonal Antibody detects endogenous levels of COX19 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：COX19;Cytochrome c oxidase assembly protein COX19;hCOX19

Molecular Weight(Da)：10kD

Background： COX19 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox19 protein may play a role in metal transport to the mitochondrial intermembrane space and assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM, Mar 2008],

Function：function:May be required for the assembly of mitochondrial cytochrome c oxidase.,similarity:Belongs to the COX19 family.,similarity:Contains 1 CHCH domain.,tissue specificity:Ubiquitously expressed. Highly expressed in skeletal muscle.,

Subcellular Location：Cytoplasm, cytosol . Mitochondrion intermembrane space . Mitochondrion . Partitions between mitochondria and the cytosol in a copper-dependent manner. Enriched in the cytosol when intracellular copper concentrations are elevated. .

Expression：Ubiquitously expressed. Highly expressed in skeletal muscle.