Target：COPT1

Fields：Platinum drug resistance;Mineral absorption

Gene Name：SLC31A1 COPT1 CTR1

Protein Name：High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1)

Human Gene Id：1317

Human Swiss Prot No：O15431

Mouse Swiss Prot No：Q8K211

Rat Swiss Prot No：Q9JK41

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：COPT1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：20kD

Background： The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011],

Function：function:Involved in high-affinity copper uptake.,PTM:O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.,similarity:Belongs to the SLC31A transporter family.,subunit:Homotrimer.,

Subcellular Location：Cell membrane; Multi-pass membrane protein. Localizes to the apical membrane in intestinal epithelial cells. .

Expression： Brain,Liver,Lung,Skeletal muscle,Skin,