Target：Copine 8

Gene Name：CPNE8

Protein Name：Copine-8

Human Gene Id：144402

Human Swiss Prot No：Q86YQ8

Mouse Gene Id：66871

Mouse Swiss Prot No：Q9DC53

Immunogen：The antiserum was produced against synthesized peptide derived from human CPNE8. AA range:11-60

Specificity：Copine 8 Polyclonal Antibody detects endogenous levels of Copine 8 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CPNE8;Copine-8;Copine VIII

Observed Band(KD)：65kD

Background：copine 8(CPNE8) Homo sapiens Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008],

Function：function:May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the copine family.,similarity:Contains 1 VWFA domain.,similarity:Contains 2 C2 domains.,

Subcellular Location：extracellular exosome,

Expression： Brain,Hippocampus,