Target:Galectin-8
Gene Name:LGALS8
Protein Name:Galectin-8
Human Gene Id:3964
Human Swiss Prot No:O00214
Mouse Gene Id:56048
Mouse Swiss Prot No:Q9JL15
Immunogen:The antiserum was produced against synthesized peptide derived from human LEG8. AA range:61-110
Specificity:Galectin-8 Polyclonal Antibody detects endogenous levels of Galectin-8 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:LGALS8;Galectin-8;Gal-8;Po66 carbohydrate-binding protein;Po66-CBP;Prostate carcinoma tumor antigen 1;PCTA-1
Observed Band(KD):36kD
Background: This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Function:domain:Contains two homologous but distinct carbohydrate-binding domains.,online information:Galectin-8 C-terminal CRD,online information:Galectin-8 long isoform,similarity:Contains 2 galectin domains.,tissue specificity:Ubiquitous. Selective expression by prostate carcinomas versus normal prostate and benign prostatic hypertrophy.,
Subcellular Location:Cytoplasmic vesicle . Cytoplasm, cytosol .
Expression:Ubiquitous. Selective expression by prostate carcinomas versus normal prostate and benign prostatic hypertrophy.