Target:Galectin-7
Gene Name:LGALS7
Protein Name:Galectin-7
Human Gene Id:3963/653499
Human Swiss Prot No:P47929
Mouse Swiss Prot No:O54974
Rat Gene Id:29518
Rat Swiss Prot No:P97590
Immunogen:The antiserum was produced against synthesized peptide derived from human LEG7. AA range:41-90
Specificity:Galectin-7 Polyclonal Antibody detects endogenous levels of Galectin-7 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:LGALS7;PIG1;LGALS7B;Galectin-7;Gal-7;HKL-14;PI7;p53-induced gene 1 protein
Molecular Weight(Da):16kD
Background: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008],
Function:function:Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.,induction:By p53.,online information:Galectin-7,similarity:Contains 1 galectin domain.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Monomer.,tissue specificity:Mainly in stratified squamous epithelium.,
Subcellular Location:Cytoplasm . Nucleus . Secreted . May be secreted by a non-classical secretory pathway.
Expression:Mainly expressed in stratified squamous epithelium.