Target:KLF13
Gene Name:KLF13
Protein Name:Krueppel-like factor 13
Human Gene Id:51621
Human Swiss Prot No:Q9Y2Y9
Mouse Gene Id:50794
Mouse Swiss Prot No:Q9JJZ6
Immunogen:The antiserum was produced against synthesized peptide derived from human KLF13 around the non-acetylation site of Lys166. AA range:131-180
Specificity:KLF13 Polyclonal Antibody detects endogenous levels of KLF13 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:KLF13;BTEB3;NSLP1;Krueppel-like factor 13;Basic transcription element-binding protein 3;BTE-binding protein 3;Novel Sp1-like zinc finger transcription factor 1;RANTES factor of late activated T-lymphocytes 1;RFLAT-1;Transcription factor BTEB3;Transcription factor NSLP1
Observed Band(KD):31kD
Background: KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008],
Function:domain:The Ala/Pro-rich domain may contain discrete activation and repression subdomains and also can mediate protein-protein interactions.,function:Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.,PTM:Phosphorylated.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,tissue specificity:Ubiquitous.,
Subcellular Location:Nucleus.
Expression:Ubiquitous.