Target:KKIAMRE
Gene Name:CDKL2
Protein Name:Cyclin-dependent kinase-like 2
Human Gene Id:8999
Human Swiss Prot No:Q92772
Mouse Swiss Prot No:Q9QUK0
Immunogen:The antiserum was produced against synthesized peptide derived from human CDKL2. AA range:211-260
Specificity:KKIAMRE Polyclonal Antibody detects endogenous levels of KKIAMRE protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CDKL2;Cyclin-dependent kinase-like 2;Protein kinase p56 KKIAMRE;Serine/threonine-protein kinase KKIAMRE
Observed Band(KD):56kD
Background: This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008],
Function:catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis and kidney, and at lower level in brain and lung.,
Subcellular Location:Cytoplasm . Nucleus .
Expression:Expressed in testis and kidney, and at lower level in brain and lung.