Target：KKIALRE

Gene Name：CDKL1

Protein Name：Cyclin-dependent kinase-like 1

Human Gene Id：8814

Human Swiss Prot No：Q00532

Mouse Swiss Prot No：Q8CEQ0

Rat Gene Id：314198

Rat Swiss Prot No：Q66HE7

Immunogen：The antiserum was produced against synthesized peptide derived from human CDKL1. AA range:281-330

Specificity：KKIALRE Polyclonal Antibody detects endogenous levels of KKIALRE protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CDKL1;Cyclin-dependent kinase-like 1;Protein kinase p42 KKIALRE;Serine/threonine-protein kinase KKIALRE

Observed Band(KD)：42kD

Background： This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013],

Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highly expressed in kidney, and to a lower extent in ovary.,

Subcellular Location：Cytoplasm . Nucleus .

Expression：Highly expressed in kidney, and to a lower extent in ovary.