Target：KANK2

Gene Name：KANK2

Protein Name：KN motif and ankyrin repeat domain-containing protein 2

Human Gene Id：25959

Human Swiss Prot No：Q63ZY3

Mouse Swiss Prot No：Q8BX02

Immunogen：The antiserum was produced against synthesized peptide derived from human KANK2. AA range:351-400

Specificity：KANK2 Polyclonal Antibody detects endogenous levels of KANK2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：KANK2;ANKRD25;KIAA1518;MXRA3;SIP;KN motif and ankyrin repeat domain-containing protein 2;Ankyrin repeat domain-containing protein 25;Matrix-remodeling-associated protein 3;SRC-1-interacting protein;SIP;SRC-interacting protein;SRC

Molecular Weight(Da)：91kD

Background： This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair. [provided by RefSeq, Jul 2016],

Function：PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 5 ANK repeats.,tissue specificity:Strongly expressed in cervix, colon, heart, kidney and lung.,

Subcellular Location：Cytoplasm . Mitochondrion .

Expression：Strongly expressed in cervix, colon, heart, kidney and lung. Expressed in kidney glomerular podocytes and mesangial cells (at protein level).