Target：Imp3

Fields：Ribosome biogenesis in eukaryotes

Gene Name：IMP3 C15orf12 MRPS4

Protein Name：IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)

Human Gene Id：55272

Human Swiss Prot No：Q9NV31

Mouse Gene Id：102462

Mouse Swiss Prot No：Q921Y2

Immunogen：Synthetic peptide from human protein at AA range: 135-184

Specificity：The antibody detects endogenous Imp3 protein

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000, ELISA 1:10000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：IMP3 C15orf12 MRPS4

Observed Band(KD)：25kD

Background： This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008],

Function：function:Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.,similarity:Belongs to the ribosomal protein S4P family.,similarity:Contains 1 S4 RNA-binding domain.,subunit:Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with MPHOSPH10.,

Subcellular Location：Nucleus, nucleolus .

Expression： Eye,Placenta,Uterus,