Target:Rab 20
Gene Name:RAB20
Protein Name:Ras-related protein Rab-20
Human Gene Id:55647
Human Swiss Prot No:Q9NX57
Mouse Swiss Prot No:P35295
Immunogen:The antiserum was produced against synthesized peptide derived from human RAB20. AA range:115-164
Specificity:Rab 20 Polyclonal Antibody detects endogenous levels of Rab 20 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RAB20;Ras-related protein Rab-20
Observed Band(KD):28kD
Background:function:Plays a role in apical endocytosis/recycling.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules.,tissue specificity:Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).,
Function:function:Plays a role in apical endocytosis/recycling.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules.,tissue specificity:Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).,
Subcellular Location:Golgi apparatus . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). .
Expression:Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).