Target：FMIP

Fields：Nucleocytoplasmic transport

Gene Name：THOC5

Protein Name：THO complex subunit 5 homolog

Human Gene Id：8563

Human Swiss Prot No：Q13769

Mouse Gene Id：107829

Mouse Swiss Prot No：Q8BKT7

Rat Gene Id：360972

Rat Swiss Prot No：Q68FX7

Immunogen：The antiserum was produced against synthesized peptide derived from human THOC5. AA range:561-610

Specificity：FMIP Polyclonal Antibody detects endogenous levels of FMIP protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：THOC5;C22orf19;KIAA0983;THO complex subunit 5 homolog;Functional spliceosome-associated protein 79;fSAP79;NF2/meningioma region protein pK1.3;Placental protein 39.2;PP39.2;hTREX90

Observed Band(KD)：78kD

Background：function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,

Function：function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,

Subcellular Location：Nucleus . Cytoplasm . Shuttles between nucleus and cytoplasm. .

Expression：Ubiquitously expressed.