Target：FLVC1

Gene Name：FLVCR1 FLVCR

Protein Name：Feline leukemia virus subgroup C receptor-related protein 1 (Feline leukemia virus subgroup C receptor) (hFLVCR)

Human Gene Id：28982

Human Swiss Prot No：Q9Y5Y0

Immunogen：Synthesized peptide derived from human protein . at AA range: 481-530

Specificity：FLVC1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：61kD

Background： This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder Diamond-Blackfan syndrome. [provided by RefSeq, Jan 2011],

Function：developmental stage:Down-regulated in haemopoietic progenitor cells undergoing differentiation and hemoglobinization. Abundant in fetal liver.,function:Exports cytoplasmic heme. May be required to protect developing erythroid cells from heme toxicity. Causes susceptibility to FeLV-C in vitro.,similarity:Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family.,tissue specificity:Found all hematopoietic tissues including peripheral blood lymphocytes. Some expression is found in pancreas and kidney.,

Subcellular Location：[Isoform 1]: Cell membrane ; Multi-pass membrane protein .; [Isoform 2]: Mitochondrion membrane ; Multi-pass membrane protein .

Expression：Found all hematopoietic tissues including peripheral blood lymphocytes. Some expression is found in pancreas and kidney.