Target:FASTKD3
Gene Name:FASTKD3
Protein Name:FAST kinase domain-containing protein 3
Human Gene Id:79072
Human Swiss Prot No:Q14CZ7
Mouse Swiss Prot No:Q8BSN9
Immunogen:The antiserum was produced against synthesized peptide derived from human FAKD3. AA range:121-170
Specificity:FASTKD3 Polyclonal Antibody detects endogenous levels of FASTKD3 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:FASTKD3;FAST kinase domain-containing protein 3
Observed Band(KD):75kD
Background: This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
Function:similarity:Belongs to the FAST kinase family.,similarity:Contains 1 RAP domain.,
Subcellular Location:Mitochondrion .
Expression:Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid.