Target：FAIM2

Gene Name：FAIM2

Protein Name：Protein lifeguard 2

Human Gene Id：23017

Human Swiss Prot No：Q9BWQ8

Mouse Swiss Prot No：Q8K097

Immunogen：Synthesized peptide derived from the N-terminal region of human FAIM2.

Specificity：FAIM2 Polyclonal Antibody detects endogenous levels of FAIM2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FAIM2;KIAA0950;LFG;LFG2;NMP35;TMBIM2;Protein lifeguard 2;Fas apoptotic inhibitory molecule 2;Neural membrane protein 35;Transmembrane BAX inhibitor motif-containing protein 2

Observed Band(KD)：35kD

Background：function:Protects cells uniquely from Fas-induced apoptosis.,similarity:Belongs to the BI1 family.,subunit:Interacts with TNFRSF6.,tissue specificity:Widely expressed. Expressed at high levels in the brain especially in the hippocampus.,

Function：function:Protects cells uniquely from Fas-induced apoptosis.,similarity:Belongs to the BI1 family.,subunit:Interacts with TNFRSF6.,tissue specificity:Widely expressed. Expressed at high levels in the brain especially in the hippocampus.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein . Membrane raft . Cell junction, synapse, postsynaptic cell membrane .

Expression：Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus.