Target：FACE2

Fields：Terpenoid backbone biosynthesis

Gene Name：RCE1 FACE2 RCE1A RCE1B

Protein Name：CAAX prenyl protease 2 (EC 3.4.22.-) (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1)

Human Gene Id：9986

Human Swiss Prot No：Q9Y256

Mouse Swiss Prot No：P57791

Rat Swiss Prot No：B0BMW8

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：FACE2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：36kD

Background： This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins. [provided by RefSeq, Jul 2008],

Function：function:Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1.,similarity:Belongs to the peptidase U48 family.,tissue specificity:Ubiquitous.,

Subcellular Location：Endoplasmic reticulum membrane ; Multi-pass membrane protein .

Expression：Ubiquitous.