Target：ESYT1

Gene Name：ESYT1 FAM62A KIAA0747 MBC2

Protein Name：Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein)

Human Gene Id：23344

Human Swiss Prot No：Q9BSJ8

Mouse Swiss Prot No：Q3U7R1

Rat Swiss Prot No：Q9Z1X1

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：ESYT1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：121kD

Background：function:May play a role as calcium-regulated intrinsic membrane protein.,similarity:Belongs to the extended synaptotagmin family.,similarity:Contains 5 C2 domains.,subcellular location:Localizes to intracellular membranes.,tissue specificity:Widely expressed.,

Function：function:May play a role as calcium-regulated intrinsic membrane protein.,similarity:Belongs to the extended synaptotagmin family.,similarity:Contains 5 C2 domains.,subcellular location:Localizes to intracellular membranes.,tissue specificity:Widely expressed.,

Subcellular Location：Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane ; Peripheral membrane protein . Localizes primarily to the endoplasmic reticulum (PubMed:29469807). Recruited to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels (PubMed:29469807, PubMed:22250200). .

Expression：Widely expressed.