Target：NPY2-R

Fields：Neuroactive ligand-receptor interaction

Gene Name：NPY2R

Protein Name：Neuropeptide Y receptor type 2

Human Gene Id：4887

Human Swiss Prot No：P49146

Mouse Swiss Prot No：P97295

Immunogen：The antiserum was produced against synthesized peptide derived from human NPY2R. AA range:1-50

Specificity：NPY2-R Polyclonal Antibody detects endogenous levels of NPY2-R protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NPY2R;Neuropeptide Y receptor type 2;NPY2-R;NPY-Y2 receptor;Y2 receptor

Observed Band(KD)：43kD

Background：function:Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.,

Function：function:Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.