Target:NOC2L
Gene Name:NOC2L
Protein Name:Nucleolar complex protein 2 homolog
Human Gene Id:26155
Human Swiss Prot No:Q9Y3T9
Mouse Swiss Prot No:Q9WV70
Immunogen:The antiserum was produced against synthesized peptide derived from human NOC2L. AA range:602-651
Specificity:NOC2L Polyclonal Antibody detects endogenous levels of NOC2L protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NOC2L;NIR;Nucleolar complex protein 2 homolog;Protein NOC2 homolog;NOC2-like protein;Novel INHAT repressor
Observed Band(KD):85kD
Background:NOC2 like nucleolar associated transcriptional repressor(NOC2L) Homo sapiens Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM, Mar 2008],
Function:similarity:Belongs to the NOC2 family.,
Subcellular Location:Nucleus, nucleoplasm. Nucleus, nucleolus. Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin-D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis.
Expression: Brain,Epithelium,Placenta,