Target：NMBR

Fields：Neuroactive ligand-receptor interaction

Gene Name：NMBR

Protein Name：Neuromedin-B receptor

Human Gene Id：4829

Human Swiss Prot No：P28336

Mouse Gene Id：18101

Mouse Swiss Prot No：O54799

Rat Gene Id：25264

Rat Swiss Prot No：P24053

Immunogen：The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270

Specificity：NMBR Polyclonal Antibody detects endogenous levels of NMBR protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NMBR;Neuromedin-B receptor;NMB-R;Epididymis tissue protein Li 185a;Neuromedin-B-preferring bombesin receptor

Observed Band(KD)：43kD

Background： This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],

Function：function:Receptor for neuromedin-B.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression：Expressed in epididymis (at protein level).