Target：Nkx-6.1

Fields：Maturity onset diabetes of the young

Gene Name：NKX6-1

Protein Name：Homeobox protein Nkx-6.1

Human Gene Id：4825

Human Swiss Prot No：P78426

Mouse Gene Id：18096

Mouse Swiss Prot No：Q99MA9

Rat Gene Id：65193

Rat Swiss Prot No：O35762

Immunogen：Synthesized peptide derived from Nkx-6.1 . at AA range: 180-260

Specificity：Nkx-6.1 Polyclonal Antibody detects endogenous levels of Nkx-6.1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NKX6-1;NKX6A;Homeobox protein Nkx-6.1;Homeobox protein NK-6 homolog A

Molecular Weight(Da)：38kD

Background： In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008],

Function：function:May be important for control of islet development and/or regulation of insulin biosynthesis.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Pancreatic beta cells.,

Subcellular Location：Nucleus .

Expression：Pancreatic beta cells.