Target：NMUR1

Fields：Neuroactive ligand-receptor interaction

Gene Name：NMUR1

Protein Name：Neuromedin-U receptor 1

Human Gene Id：10316

Human Swiss Prot No：Q9HB89

Mouse Swiss Prot No：O55040

Immunogen：The antiserum was produced against synthesized peptide derived from human NMUR1. AA range:1-50

Specificity：NMUR1 Polyclonal Antibody detects endogenous levels of NMUR1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NMUR1;GPR66;Neuromedin-U receptor 1;NMU-R1;G-protein coupled receptor 66;G-protein coupled receptor FM-3

Observed Band(KD)：48kD

Background：caution:It is uncertain whether Met-1 or Met-24 is the initiator.,function:Receptor for the neuromedin-U and neuromedin-S neuropeptides.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.,

Function：caution:It is uncertain whether Met-1 or Met-24 is the initiator.,function:Receptor for the neuromedin-U and neuromedin-S neuropeptides.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.