Target:NK-TR
Gene Name:NKTR
Protein Name:NK-tumor recognition protein
Human Gene Id:4820
Human Swiss Prot No:P30414
Mouse Swiss Prot No:P30415
Immunogen:The antiserum was produced against synthesized peptide derived from human NKTR. AA range:784-833
Specificity:NK-TR Polyclonal Antibody detects endogenous levels of NK-TR protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NKTR;NK-tumor recognition protein;NK-TR protein;Natural-killer cells cyclophilin-related protein
Molecular Weight(Da):166kD
Background: This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells. [provided by RefSeq, Jul 2008],
Function:catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,function:Component of a putative tumor-recognition complex. Involved in the function of NK cells.,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcellular location:Attached to the membrane via its N-terminus.,
Subcellular Location:Cell membrane .
Expression: Aorta endothelial cell,Blood,Epithelium,Fetal kidney,Human endometr