Target：NKp46
Fields：Natural killer cell mediated cytotoxicity
Gene Name：NCR1
Protein Name：Natural cytotoxicity triggering receptor 1
Human Gene Id：9437
Human Swiss Prot No：O76036
Mouse Swiss Prot No：Q8C567
Immunogen：The antiserum was produced against synthesized peptide derived from human NCR1. AA range:145-194
Specificity：NKp46 Polyclonal Antibody detects endogenous levels of NKp46 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：NCR1;LY94;Natural cytotoxicity triggering receptor 1;Lymphocyte antigen 94 homolog;NK cell-activating receptor;Natural killer cell p46-related protein;NK-p46;NKp46;hNKp46;CD antigen CD335
Observed Band(KD)：40kD
Background：function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,
Function：function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,
Subcellular Location：Cell membrane ; Single-pass type I membrane protein .
Expression：Selectively expressed by both resting and activated NK cells.
