Target:NKp44
Fields:Natural killer cell mediated cytotoxicity
Gene Name:NCR2
Protein Name:Natural cytotoxicity triggering receptor 2
Human Gene Id:9436
Human Swiss Prot No:O95944
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human NCR2. AA range:61-110
Specificity:NKp44 Polyclonal Antibody detects endogenous levels of NKp44 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NCR2;LY95;Natural cytotoxicity triggering receptor 2;Lymphocyte antigen 95 homolog;NK cell-activating receptor;Natural killer cell p44-related protein;NK-p44;NKp44;CD336
Observed Band(KD):44kD
Background:function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,subunit:Interacts with TYROBP/DAP12.,tissue specificity:Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.,
Function:function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,subunit:Interacts with TYROBP/DAP12.,tissue specificity:Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.,
Subcellular Location:Cell membrane ; Single-pass type I membrane protein .
Expression:Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.